福建医科大学基础医学院

陶武成教授

作者:2021/09/27 07:10

博、硕士研究生导师简介



个人简历:

  

  

       陶武成,生理学博士。福建医科大学基础医学院教授,博导,基础医学院副院长。福建省“百人计划”海外引进人才,“闽江学者”特聘教授。博士毕业于美国华盛顿大学 (University of Washington), 随后在加州大学旧金山分校从事博士后研究,师从美国科学院院士Roger Nicoll教授。应用电生理,分子生物学及光遗传学等方法系统地研究离子通道,受体,突触传递,环路功能,以及整体动物行为,来阐述大脑功能及相关疾病。目前的课题涉及:(1)离子通道和受体的生物物理特性,生理功能及药理;2)神经突触传递的分子机制及信号转导;(3)突触可塑性;(4)学习与记忆;5)学习与记忆异常相关的疾病,比如老年痴呆症。目前已发表SCI论文10篇,其中以第一作者在PNASIF=10)、Molecular PsychiatryIF=13.6,封面文章)等国际知名杂志发表4篇论文,相关成果曾被Nature Review Neuroscience等杂志重点推荐和评论。在FrontiersIF=4.0)等杂志担任审稿编委。

发表文章:

(1)Tao, Wucheng; Ma, Chenxue; Bemben, Michael A; Li, Kathy H; Burlingame, Alma L; Zhang, Mingjie; Nicoll, Roger A*Mechanisms underlying the synaptic trafficking of the glutamate delta receptor GluD1 , Molecular Psychiatry, 2019, 24(10): 1451-1460. Cover Paper

(2)Tao Wucheng; Diaz Alonso Javier; Sheng Nengyin; Nicoll Roger A*Posts ynaptic delta 1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin , Proceedings of the National Academy of Sciences of the United States of America, 2018, 115(23): E5373-E5381.

(3)Duan Gui-Fang; Ye Yaxin; Xu Sha; Tao Wucheng; Zhao Shiping; Jin Tengchuan; Nicoll Roger A; Shi Yun Stone*; Sheng Nengyin*Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino- terminal domain. , Nature Communications, 2018, 9(1): 0-4879.

(4)Sheng Nengyin; Bemben Michael A; Diaz Alonso Javier; Tao Wucheng; Shi Yun Stone; Nicoll Roger A*LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes , Proceeding s of the National Academy of Sciences of the United States of America, 2018, 115(15): 3948-3953.

(5)Tao Wucheng; Higgs Matthew H; Spain William J; Ransom Christopher B*Postsynaptic GABA(B) Receptors Enhance Extrasynaptic GABA(A) Receptor
 Function in Dentate Gyrus Granule Cells 
, Journal of Neuroscience, 2013, 33(9) : 3738-3743.

(6)Ransom Christopher B*Tao Wucheng; Wu Yuanming; Spain William J; Richerson George B; Rapid regulation of tonic GABA currents in cultured rat hippocampal neurons , Journal of Neurophysiology, 2013, 109(3): 803-812.

(7)Li, Mengtao; Chen, Minhui; Huang, Hai; Tao, Wucheng; Cui, Jihong; Xiang, Hui*Neuroprotective Effects of Active Ingredients Isolated from Pegasus laternarius on Cultured Cerebral Neurons , Cellular and Molecular Neurobiology, 2011, 31(1): 73-82.

(8)Cui, Jihong; Hu, Wen; Cai, Zhanjun; Liu, Yingxue; Li, Siyuan; Tao, Wucheng; Xiang, Hui*New medicinal properties of mangostins: Analgesic activity and pharmacological characterization of active ingredients from the fruit hull of Garcinia mangostana L. , Pharmacology Biochemistry and Behavior , 2010, 95(2): 166-172.

(9)Wang, Ke; Cui, Jihong; Cai, Yijun; Wang, Fang; Li, Yi; Tao, Wucheng; Xiang, Hui*Critical Roles of Voltage-Dependent Sodium Channels in the Process of Synaptogenesis During the Postnatal Cortical Development of Rats , Cellular and Molecular Neurobiology, 2009, 29(8): 1131-1142.

(10)Xiang Hui#*; Tao Wucheng#; Wang Lei#; Wang Fang#; Xu Anlong; The Effect of Recombinant Neurotoxins from the Sea Anemone Anthopleura sp on Sodium Currents of Rat Cerebral Cortical Neurons , Cellular and Molecular Neurobiology, 2008, 28(8): 1119-1128.

(更新于2021年9月)


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