福建医科大学基础医学院

陶武成

作者:2019/12/31 03:28

博、硕士研究生导师简介

(更新于2022年3月23日)



个人简历:

    陶武成,生理学博士。福建医科大学基础医学院教授、博导、副院长。福建省“百人计划”海外引进人才,“闽江学者”特聘教授。博士毕业于美国华盛顿大学 (University of Washington), 随后在加州大学旧金山分校从事博士后研究,师从美国科学院院士Roger Nicoll教授。应用电生理,分子生物学及光遗传学等方法系统地研究离子通道、受体、突触传递、环路功能以及整体动物行为,来阐述大脑功能及相关疾病。目前的课题涉及:(1)离子通道和受体的生物物理特性,生理功能及药理;(2)神经突触传递的分子机制及信号转导;(3)突触可塑性;(4)学习与记忆;(5)学习与记忆异常相关的疾病,比如老年痴呆症。目前已发表SCI论文12篇,其中包括以第一作者在PNAS(IF=10)、Molecular Psychiatry(IF=15.9,封面文章)、ElifeJ of Neuorscience等国际知名杂志发表5篇论文,相关成果曾被Nature Review Neuroscience等杂志重点推荐和评论。在Frontiers(IF=4.0)等杂志担任审稿编委。

代表文章:

    (1)Tao,Wucheng; Lee, J; Chen, X; Diaz-Alonso, J; Zhou, J; Pleasure, S; Nicoll, RA ; Synaptic memory requires CaMKII, Elife, 2021, 10.

    (2)Tao, Wucheng; Ma, Chenxue; Bemben, Michael A; Li, Kathy H; Burlingame, Alma L; Zhang, Mingjie; Nicoll, Roger A; Mechanisms underlying the synaptic trafficking of the glutamate delta receptor GluD1 , Molecular Psychiatry, 2019, 24(10): 1451-1460. Cover Paper

    (3)Tao, Wucheng; Diaz, Alonso Javier; Sheng, Nengyin; Nicoll, Roger A; Posts ynaptic delta 1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin , Proceedings of the National Academy of Sciences of the United States of America, 2018, 115(23): E5373-E5381.

    (4)Tao, Wucheng; Higgs, Matthew H; Spain, William J; Ransom, Christopher B; Postsynaptic GABA(B) Receptors Enhance Extrasynaptic GABA(A) Receptor

Function in Dentate Gyrus Granule Cells , Journal of Neuroscience, 2013, 33(9) : 3738-3743.

    (5)Xiang, Hui#; Tao, Wucheng#; Wang, Lei#; Wang, Fang#; Xu, Anlong; The Effect of Recombinant Neurotoxins from the Sea Anemone Anthopleura sp on Sodium Currents of Rat Cerebral Cortical Neurons , Cellular and Molecular Neurobiology, 2008, 28(8): 1119-1128. (#co-first author)


其他文章: 

    (1) Li, Ning ; Tao , Wucheng; Yang, Liu ; Spain , William J ; Ransom, Christopher B; GABA-B receptors enhance GABA-A receptor currents by modulation of membrane trafficking in dentate gyrus granule cells, Neurosci Lett, 2022 Mar 16;773:136481.

    (2)Duan, Gui-Fang; Ye, Yaxin; Xu, Sha; Tao, Wucheng; Zhao, Shiping; Jin, Tengchuan; Nicoll, Roger A; Shi, Yun Stone; Sheng, Nengyin; Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino- terminal domain. , Nature Communications, 2018, 9(1): 0-4879.

    (3)Sheng, Nengyin; Bemben, Michael A; Diaz, Alonso Javier; Tao, Wucheng; Shi, Yun Stone; Nicoll, Roger A; LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes , Proceeding s of the National Academy of Sciences of the United States of America, 2018, 115(15): 3948-3953.

    (4)Ransom, Christopher B; Tao, Wucheng; Wu, Yuanming; Spain, William J; Richerson, George B; Rapid regulation of tonic GABA currents in cultured rat hippocampal neurons , Journal of Neurophysiology, 2013, 109(3): 803-812.

    (5)Li, Mengtao; Chen, Minhui; Huang, Hai; Tao, Wucheng; Cui, Jihong; Xiang, Hui; Neuroprotective Effects of Active Ingredients Isolated from Pegasus laternarius on Cultured Cerebral Neurons , Cellular and Molecular Neurobiology, 2011, 31(1): 73-82.

    (6)Cui, Jihong; Hu, Wen; Cai, Zhanjun; Liu, Yingxue; Li, Siyuan; Tao, Wucheng; Xiang, Hui; New medicinal properties of mangostins: Analgesic activity and pharmacological characterization of active ingredients from the fruit hull of Garcinia mangostana L. , Pharmacology Biochemistry and Behavior , 2010, 95(2): 166-172.

    (7)Wang, Ke; Cui, Jihong; Cai, Yijun; Wang, Fang; Li, Yi; Tao, Wucheng; Xiang, Hui; Critical Roles of Voltage-Dependent Sodium Channels in the Process of Synaptogenesis During the Postnatal Cortical Development of Rats , Cellular and Molecular Neurobiology, 2009, 29(8): 1131-1142. 




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