福建医科大学基础医学院

王先龙

作者:2019/12/31 05:15


博、硕士研究生导师简介


个人简介:

王先龙,博士,福建医科大学生物信息学系教授。2006年于美国布林莫尔学院化学系获得哲学博士(PhD)学位。2008年至2017年在电子科技大学任教,2017年调入福建医科大学工作。主要研究领域为生物信息学和计算生物学,重点关注肿瘤标志物发现和药物基因组学研究,特别是中枢神经系统肿瘤的诊断和治疗。已在国际学术期刊上发表SCI检索论文40余篇(第一作者或通讯作者共二十余篇),出版英文学术专著一本,主持国家自然科学基金青年基金一项,主研国家自然科学基金重点项目一项,主持教育部博士点基金一项,主持成都市中小企业创新基金一项,主持研发了多款科学计算软件。在教学方面,承担多项校级教改项目,发表多篇教学论文,出版教材一部,获得多项校级和省级教学成果奖,作为教练带领本科生参加国际基因遗传工程机器大赛(iGEM),获得软件队金牌。

  

科研工作:

科研项目

1.2007.062008.06 主持成都高新区科技局中小企业创新项目,25万元

2.2011.012013.12 主持教育部高等学校博士点专项基金新教师基金,3.6万元

3.2012.012014.12 主持国家自然科学基金委青年基金项目,25万元

4.2016.122020.12 主研国家自然科学基金委重点项目,358万元(1/10

5.2019.072022.06 主持福建省自然科学基金项目,10万元

近期论文:

    1.Qingzhou Guan, Haidan Yan, Yanhua Chen, Baotong Zheng, Hao Cai, Jun He, Kai Song, You Guo, Lu Ao, Huaping Liu, Wenyuan Zhao, Xianlong Wang* and Zheng Gu*. Quantitative or qualitative transcriptional diagnostic signatures? A case study for colorectal cancer. BMC Genomics. 2018, 19:99 (DOI: 10.1186/s12864-018-4446-y) (JCR二区,IF3.729)

    2.Hao Cai, Xiangyu Li, Jing Li, Qirui Liang, Weicheng Zheng, Qingzhou Guan, Zheng Guo*, Xianlong Wang*. Identifying differentially expressed genes from cross-site integrated data based on relative expression orderings. Int. J. Biol. Sci.2018,14(8):892-900. (DOI:10.7150/ijbs.24548) (JCR 三区, IF 3.873

    3.Jun Cheng, Xuekun Song, Lu Ao, Rou Chen, Meirong Chi, You Guo, Jiahui Zhang, Hongdong Li, Wenyuan Zhao, Zheng Guo*, Xianlong Wang*. Shared liver-like transcriptional characteristics in liver metastases and corresponding primary colorectal tumors. J. Cancer2018, 9(8):1500-1505. (DOI:10.7150/jca.23017) (JCR三区,IF2.916)

    4.Lu Ao, Zimei Zhang, Qingzhou Guan, Yating Guo, You Guo, Jiahui Zhang, Xingwei Lv, Haiyan Huang, Huarong Zhang, Xianlong Wang, Zheng Guo. A qualitative signature for early diagnosis of hepatocellular carcinoma based on relative expression orderings. Liver International.2018, 38, 18121819. (DOI: 10.1111/liv.13864) (JCR二区,IF4.116)

    5.Huaping Liu, Yawei Li, Jun He, Qingzhou Guan, Rou Chen, Haidan Yan, Weicheng Zheng, Kai Song, Hao Cai, You Guo, Xianlong Wang* and Zheng Guo*. Robust transcriptional signatures for low-input RNA samples based on relative expression orderings. BMC Genomics. 2017,18:913. (DOI: 10.1186/s12864-017-4280-7) (JCR二区,IF3.729)

    6.Jun He, Haidan Yan, Hao Cai, Xiangyu Li, Qingzhou Guan, Weicheng Zheng, Rou Chen, Huaping Liu, Kai Song, Zheng Guo* and Xianlong Wang*. Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning. Journal of Translational Medicine.2017,15:198. (DOI: 10.1186/s12967-017-1302-9). (JCR二区,IF3.786)

    7.Lu Ao, You Guo, Xuekun Song, Qingzhou Guan, Weicheng Zheng, Jiahui Zhang, Haiyan Huang, Yi Zou, Zheng Guo*, Xianlong Wang*. Evaluating hepatocellular carcinoma cell lines for tumor samples using within-sample relative expression orderings of genes. Liver International. 2017, 37, 1688-1696. (DOI: 10.1111/liv.13467). (JCR二区,IF4.116)

    8.Shuqin Cao, Yanpeng Liu, Hui Shang, Sheyu Li, Jian Jiang, Xiaofeng Zhu*, Peng Zhang, Xianlong Wang*, Jianshu Li*.  Supramolecular nanoparticles of calcitonin and dipeptide for long-term controlled release. Journal of Controlled Release.2017, 256(28):182-192. (DOI: 10.1016/j.jconrel.2017.04.014). (JCR一区,IF7.441)

    9.Peter A Beckmann*, Clelia W Mallory, Frank B Mallory, Arnold L Rheingold, Xianlong Wang*. Methoxy and Methyl Group Rotation: Solid-State NMR 1H Spin-Lattice Relaxation, Electronic Structure Calculations, X-ray Diffractometry, and Scanning Electron Microscopy. ChemPhysChem, 2015, 16(7), 1509. DOI: 10.1002/cphc.201402716 (二区, IF3.138)

    10.Xianlong Wang*, Frank B Mallory, Clelia W Mallory, Hosanna Odhner, Peter A Beckmann*. Solid state 1H spin-lattice relaxation and isolated-molecule and cluster electronic structure calculations in organic molecular solids: The relationship between structure and methyl group and t-butyl group rotation. J. Chem. Phys. 2014, 140(19), 194304. DOI: 10.1063/1.4874157 (二区, IF2.894)

  

  

教学工作:

主持三项校级教学改革项目,发表教学论文4篇,获校、省级教学成果奖,出版教材一部。作为教练带领本科生参加国际基因遗传工程机器大赛(iGEM),多次获得软件队金牌。

  

学术活动:

中国抗癌协会肿瘤标志委员会基因测序及大数据分析协作组委员,福建省生物信息学会筹备组成员。


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